Dr. Mandi Lopez- LSU SVM Faculty

Dr. Mandi Lopez

Professor - Director Laboratory for Equine and Comparative Orthopedic Research

Veterinary Clinical Sciences (VCS)

(225) 578-9551

Biography:
Dr. Lopez is from the Pacific Northwest. She received her bachelor's degree from Humboldt State University in Arcata, California and attended veterinary school at the University of California, Davis. She completed a food animal internship at Kansas State University prior to going to the University of Wisconsin, where she completed a residency in large animal surgery and obtained MS and PhD degrees. She then did a post-doctoral fellowship in applied biomechanics. Her areas of interest are within comparative orthopedic research and surgery. Dr. Lopez is board certified by the American College of Veterinary Surgeons. Dr. Lopez has several patents for biomedical devices and has expertise in both applied and basic research. She came to LSU in January 2004 and directs the Laboratory of Equine and Comparative Orthopedic Research (LECOR).

Teaching Interests:
Biomechanics Stem Cell Biology Fracture Healing

Research Interests:
Adult Stem Cell Applications Orthopedic Implants Kinetics/kinematics Anterior Cruciate Ligament Rupture Laminitis Hip Dysplasia

Awards & Honors:

2017 Exellence in Innovation Award
2017 Subject of National Publication Cover Story
2017 National Academy of Inventors Fellow
2017 Faculty Distinguished Scholar Award
2017 Certificate
2016 National Academy of Inventors Fellow
2016 Recognition of Patent Issue - 9,044,315
2015 Fellows Program Nomination
2015 First Place (PhD Student Competition) Phi Zeta Research Day Poster Competition
2015 Recognition of Patent Issue - 8,603,115
2014 Poster Award
2014 Discover Scholar
2014 Fellows Program Nomination
2014 Fourth Place (House Officer, MS, DVM Student Competition) Phi Zeta Research Day Poster Competition
2014 Third Place (PhD Student Competition) Phi Zeta Research Day Poster Competition
2013 Poster Award
2013 Discover Scholar
2013 Fourth Place (PhD Student Competition) Phi Zeta Research Day Poster Competition
2013 Second Place Phi Zeta Research Day Poster Competition
2013 Third Place (tie) Phi Zeta Research Day Poster Competition
2013 Zoetis Award for Veterinary Research Excellence
2012 American College of Veterinary Surgeons
2012 Second Place Medical Student Research Day
2012 First Place (Tie) Phi Zeta Research Day Poster Competition
2012 First Prize (Tie) Phi Zeta Research Day Poster Competition
2010 Louisiana State University
2009 LSU Department of Economic Development
2006 American College of Veterinary Surgeons Board of Regents
2003 Arthritis Foundation
2002 Morris Animal Foundation
2001 Arthritis Foundation
2001 School of Veterinary Medicine, University of Wisconsin-Madison
2001 University of Wisconsin- Madison
2001 University of Wisconsin-Madison
1993 American Board of Veterinary Practitioners
1993 Senior Student Surgery Award
1993 University of California-Davis Chapter
1992 The American Board of Veterinary Practitioners
1991 Achievement Rewards for College Scientists Foundation
1991 School of Veterinary Medicine, University of California-Davis
1990 Scholarship
1988 Humboldt State University

Education:

PhD University of Wisconsin-Madison
MS University of Wisconsin-Madison -
DVM University of California-Davis
BS Humboldt State University

Grants:

DB Free - Functional Pancreatic Cells from Feline Adipose Tissue, LSU LIFT2, $42,180.00
De Novo Generation of Canine Cranial Cruciate Ligament Using Infrapatellar Adipose Tissue-Derived Multipotent Stromal Cells , VCS Corp, $5,000.00
Quantification of Bone Motion in Normal and Laminitic Equine Hooves to Design and Optimize Stabilization Strategies, SVM CORP, USDA 1433, $7,500.00
Safety and efficacy of 117m Sn colloid for treatment of canine osteoarthritis, (re-injection study), R-NAV, LLC, $35,000.00
Equine Multipotent Stromal Cell Immobilization by Self-Assembling Peptide Scaffolds, LSU Equine Health Studies Program, $6,000.00
Investigation of Decellularized Equine Hoof Tissue Scaffold to Direct Stem Cells , LSU Equine Health Studies Program, $6,000.00
LSUHSC-NO Pig Study, LSU HSC, $125,022.00
Safety and efficacy of 117m Sn colloid for treatment of canine osteoarthritis, (bilateral elbow injection study), R-NAV, LLC, $30,468.00
Generation of insulin producing tissue grafts from adult stem cells to treat feline diabetes , Winn Feline Foundation, $23,825.00
Safety and efficacy of 117m Sn colloid for treatment of canine osteoarthritis (extension of original project), R-NAV, LLC, $20,312.00
Effect of Agmatine Supplementation on pain from intervertebral disk disease and Coxofemoral Osteoarthritis in Dogs, AHVMF and Gilad & Gilad,
Effect of an Oral Supplement Containing Curcumin Extract (Longvida) on Lameness due to Osteoarthritis or Degenerative Disease and Gastric Ulcer Scores, W. F. Young Company, $161,131.00
Safety and efficacy of 117m Sn colloid for treatment of canine osteoarthritis, R-NAV, LLC, $236,144.00
Craniofacial Tissue Engineering, National Institutes of Health, $324,736.00
Effect of cranial flexion of pelvic limbs on interlaminar length of lumbosacral space in sternally and laterally recumbent swine , LSU VCS CORP Grant, $1,552.00
A reproducible protocol to identify progenitor cells for feline diabetes therapy, Merial Summer Scholars Program, $5,000.00
Agmatine supplementation for painful thoracolumbar intervertebral disc disease in dogs, American Holistic Veterinary Medical Foundation, $29,850.00
Characterization of adult equine stem cells from normal and laminitic hooves, USDA, $7,500.00
GrabTen - Innovative soft tissue tensioning and fixation device, LSU Board of Supervisors LIFT2, $36,783.00
EpiBone graft dosing study-supplement, EpiBone, $53,281.25
EpiBone Graft Dosing Study, EpiBone, $180,943.00
PAH-100 to improve hind limb use in dogs with coxofemoral joint disease, Piedmont Animal Health, $126,420.00
Isolation and characterization of adult equine stem cells from normal and laminitic hooves, LSU Equine Health Studies Program, $6,000.00
Clinical assessment of extracorporeal shock wave therapy after stifle surgery in dogs, VCS CORP , $4,000.00
A reproducible protocol to identify progenitor cells for feline diabetes therapy, VCS CORP, $4,000.00
Identification of a synergistic cell immunophenotype to augment de novo bone generation by equine adipose derived multipotent stromal cells, LSU Equine Health Studies Program, $8,000.00
A revolutionary mechanism to support cutting-edge discoveries to prevent and treat degenerative hip disease, LSU-Health Sciences Center , $8,000.00
Identifying phenotypes in canine hip dysplasia, Merial - Summer Scholars Program, $5,000.00
A reproducible protocol to isolate a characterized population of adult feline adipose derived multipotent stromal cells, Veterinary Clinical Sciences Corp, $4,000.00
Selecting adipose-derived stromal cells for osteogenesis with fluorescence-activated cell sorting, LSU School of Veterinary Medicine Equine Health Studies Program, $12,000.00
Shoe shape affects motion of the distal phalanx in normal and laminitic hooves, LSU School of Veterinary Medicine Equine Health Studies Program, $6,000.00
An open source equine computer model for locomotor and veterinary research, Royal Society International Exchanges, $15,000.00
A Reproducible Protocol to Isolate a Characterized Population of Adult Feline Progenitor Cells - Continuation, Winn Feline Foundation, $23,325.00
Forces of Horses: A quantitative and 3-dimensional equine model, Louisiana Board of Regents Pilot Funding for New Research (PFUND), $10,000.00
Forces of Horses: A computer model to pair horses with patients for therapeutic riding, Equine Health Studies Program, $12,000.00
Shoe shape affects motion of the distal phalanx (P3) in normal and laminitic equine hooves: Three dimensional models of P3 motion within the hoof, Veterinary Clinical Sciences Corp, $2,000.00
Loading adult equine multipotent stromal cells onto customized scaffold by perfusion bioreactor system for cell osteogenesis, LSU School of Veterinary Medicine Equine Health Studies Program, $6,000.00
A novel in vitro model of equine hoof stem cells for laminitis research, Merial - Summer Scholars Program, $5,000.00
Post-doctoral training Fellowship , People’s Republic of China, $40,000.00
Alcohol HIV Infections & Host defense , NIH - Subcontract LSU - Health Sciences Cener, $15,874.00
Customized scaffold carrier for adult equine multipotent stromal cell osteogenesis, Louisiana State University Equine Health Studies Program, $6,000.00
Micro-Computed Tomography to Enhance Teaching & Research, Louisiana State Board of Regents, $302,000.00
Tenogenic differentiation of adult equine multi-potent stromal cells , Louisiana State University Equine Health Studies Program, $6,000.00
Localization and Characterization of Progenitor Cells in the Equine Laminitic Hoof: A New Direction in Laminitis Research, Merial - Summer Scholars Program, $5,000.00
Demineralized Bone Matrix with Syngeneic Adult Adipose Multipotent StromalCells Accelerates Spinal Fusion Compared to Demineralized Bone Matrix Alone in an Athymic Rat Model, Allosource, $108,303.00
Study number T8FUS120011:Efficacy of transdermal fentanyl to alter lameness parameters in mature horses , Elanco Animal Health, $46,300.00
Pilot Efficacy Study: Efficacy of IV fentanyl to improve lameness parameters in the horse , Elanco Animal Health , $46,885.00
Alcohol HIV Infections & Host defense , NIH - Subcontract LSU - Health Sciences Cener, $15,300.00
Identification of the Optimal Multipotent Stromal (Stem) Cell, American Kennel Club Canine Heath Foundation, $12,000.00
Elucidation of the Roles of MiR203 and Mitochondrial denovo Fatty Acid Synthesis in Equine Laminitis, Louisiana State University Equine Health Studies Program, $12,000.00
Desmoglein Proteins in Equine Hoof Laminae: Finding a Stem Cell Soution for Laminitis, Morris Animal Foundation, $4,000.00
Personalized Bone Grafts for Craniofacial Reconstruction, New York City Economic Development Foundation, $107,894.00
A Reproducible Protocol to Isolate a Characterized Population of Adult Feline Progenitor Cells, Winn Feline Foundation, $10,000.00
Efficacy of an Oral Herbal Supplement for Treatment of Horses with Lameness due to Osteoarthritis or Degenerative Joint Disease, Central Life Sciences, $99,062.00
Isolation and In Vitro Expansion and Differentiation of Adult Equine Laminar Stem Cells from Normal and Laminitic Horses, LSU SVM USDA, $7,000.00
In Vitro Tissue Generation by Adult Equine Multipotent Stromal Cells on Collagen Scaffolds, LSU Equine Health Studies Program, $12,000.00
Modifications of Equine Laminar Cells due to Laminitis, LSU Equine Health Studies Program, $6,000.00

Publications:
Journal Article, Professional Journal:

Canine hip dysplasia: a natural model for human developmental dysplasia of the hip, Pascaul-Garrido, C; Guilak, F; Rai, M; Harris, M; Lopez, Mandi; Todhunter, R; Clohisy, J, 2017, J Orthop Res
Collagen and hydroxyapatite scaffolds activate distinct osteogenesis signaling pathways in adult adipose-derived multipotent stromal cells, Duan, Wei; Haque, Masudal; Kearney, Michael; Lopez, Mandi, 2017, Tiss Eng Part C Methods , Volume: 23, Number: 10, Pages: 592-603
A needle probe to detect surface enhanced raman scattering (SERS) within solid specimens, Basu, S; Hou, H; Biswas, D; Daniels-Race, Theda; Lopez, Mandi; Mathis, J. Michael; Feldman, Martin, 2017, Review of Scientific Instruments , Volume: 88, Number: 2
A needle probe to detect surface enhanced raman scattering (SERS) within solid specimens, Basu, S; Hou, H; Biswas, D; Maulik, S; Daniels-Race, Theda; Lopez, Mandi; Mathis, J. Michael; Feldman, Martin, 2017, Rev Sci Instrum , Volume: 88, Number: 2
Tissue engineered autologous grafts for facial bone reconstruction, Bhumiratana, S; Bernhard, J; Alfi, D; Yeager, K; Eton, R; Bova, J; Shah, F; Gimble, J; Lopez, Mandi; Eisig, S; Vunjak-Novakovic, G, 2016, Sci Transl Med , Volume: 8, Pages: 343ra83
Gait changes vary among horses with naturally occurring osteoarthritis following intra-articular administration of autologous platelet-rich plasma, Mirza, Mustajab; Bommala, Prakash; Richbourg, Heather; Rademacher, Nathalie; Kearney, Michael; Lopez, Mandi, 2016, Front Vet Science
Bupivacaine mandibular nerve block affects intraoperative blood pressure and heart rate in a Yucatan Miniature swine condylectomy model: A Pilot Study , Stout, Rhett; Bova, Jonathan; da Cunha, Anderson; Bhumiratana, Sarindr; Alfi, David; Eisig, Sidney; Vunjak-Novakavic, Gordana; Lopez, Mandi, 2015, Journal of Investigative Surgery , Volume: 28, Number: 1, Pages: 32-39
Comparison of infrapatellar and subcutaneous adipose tissue stromal vascular fraction and stromal/stem cells in osteoarthritic subjects , Lopez, Mandi; Carvalho, P; Hamel, K; Dasa, V; Duarte, R; Porretta, C; Haque, M; Dietrich, Marilyn; Wu, X; Shah, F; Burke, D; Reis, R; Zhang, P; Gimble, J, 2014, Journal of Tissue Engineering and Regenerative Medicine , Volume: 8, Number: 10, Pages: 757-762
Therapeutic Doses of Multipotent Stromal Cells from Minimal Adipose Tissue - e pub ahead of print, Lopez, Mandi; Zhang, Nan; Dietrich, Marilyn, 2014, Stem Cell Rev Rep
Adult Multipotent Stromal Cell Technology for Bone Regeneration: A Review , Lopez, Mandi; Daigle, P, 2013, Vet Surg , Volume: 42, Number: 1, Pages: 1-11
In vitro expansion and differentiation of fresh and revitalized adult canine bone marrow-derived and adipose tissue-derived stromal cells, Lopez, Mandi; Spencer, N; Chun, R; Vidal, M; Gimble, J, 2012, Vet Journal , Volume: 191, Number: 2, Pages: 231-239
Effects of athletic conditioning on horses with degenerative suspensory ligament desmitis: A preliminary report, Lopez, Mandi; Xie, L; Spencer, N; Beadle, R; Gaschen, L; Buchert, M, 2011, Vet Journal , Volume: 189, Number: 1, Pages: 49-57
Impaired expansion and multipotentiality of adult stromal cells in a rat chronic alcohol abuse model, Lopez, Mandi; Huff, N; Spencer, N; Gimble, J; Bagby, G; Nelson, S, 2011, Alcohol , Volume: 45, Number: 4, Pages: 393-402
Biocompatible/bioabsorbable silver nanocomposite coatings, Lopez, Mandi; Qureshi, A; Monroe, W; Janes, M; Dasa, V; Hayes, D, 2011, J Applied Polymer Science , Volume: 120, Number: 5, Pages: 3042-3053
Effects of extracorporeal shock wave therapy on healing in desmitis of the accessory ligament of the deep digital flexor tendon in the horse, Lopez, Mandi; Waguespack, R; Burba, D; Hubert, J; Vidal, M; Lomax, L; Chirgwin, S, 2011, Vet Surg , Volume: 40, Number: 4, Pages: 450-456
Relationships of hip joint volume ratios with joint laxity and radiographic osteoarthritis from youth to maturity in a canine population predisposed to hip osteoarthritis, Lopez, Mandi; D'amico, L; Xie, L; Abell, L; Brown, K, 2011, Am J Vet Res , Volume: 72, Number: 3, Pages: 376-383
Adult Mesenchymal Stromal Cells: Past, Present, and Future, Lopez, Mandi; Spencer, N; Gimble, J, 2011, Vet Surg , Volume: 40, Number: 2, Pages: 129-139
Adipose tissue as a stem cell source for musculoskeletal regeneration, Lopez, Mandi; Gimble, J; Grayson, W; Guilak, F; Vunjak-Novakovic , G, 2011, Front Biosci (Schol Ed) , Volume: 1, Number: 3, Pages: 69-81
Canine stifle disease: Time for a paradigm shift? , Lopez, Mandi, 2010, Vet Surg , Volume: 39, Number: 3, Pages: 269
Ex vivo comparison of three surgical techniques to stabilize canine cranial cruciate ligament deficient stifles, Lopez, Mandi; Snow, L; White, R; Gustafson, S; Xie, l; Hosgood, G; Monroe, W; Casey, J, 2010, Vet Surg , Volume: 39, Number: 2, Pages: 195-207

Scientific Abstract:

Polymer-Mineral Scaffold to Augment in Vivo Equine Multipotent Stromal Cell Osteogenesis, Duan, Wei; Chen, Cong; Haque, Masudul; Hayes, Daniel; Lopez, Mandi, 2017
Autologous Adipose Derived Multipotent Stromal Cells on Xenografts Reduce the Systemic Lymphocyte Response, Takawira, C; Bova, J; Stout, Rhett; Dietrich, Marilyn; Lopez, Mandi, 2017
Equine Stem Cells from Laminitic Hooves Have Ectodermal and Mesodermal Characteristics, Yang, Q; Duan, W; Zhang, N; Lopez, Mandi, 2017
Polymer-Mineral Scaffold Augments in Vivo Equine Multipotent Stromal Cell Osteogenesis, Duan, Wei; Chen, Cong; Haque, Masudul; Hayes, Daniel; Lopez, Mandi, 2017
A Single Fiber Surface Enhanced Raman Scattering (SERS) Probe, Basu, S; Hou, HC; Biswas, T; Daniels-Race, Theda; Lopez, Mandi; Mathis, J. Michael; Feldman, Martin, 2017
Chronic alcohol consumption alters adult stromal cell expansion, multipotentiality, gene expression and lumbar vertebral trabecular bone in a dose dependent manner, Terhoeve, C; Xiao, j; Feng, D; Fargason, C; Lopez, Mandi, 2017
Feline adipose derived multipotent stromal cells express major histocompatibility complex II and have ectodermal transdifferentiation capacity, Duan, Wei; Dietrich, Marilyn; Lopez, Mandi, 2017
Scaffold composition directs osteogenic signaling in adult adipose-derived multipotent stromal cell osteogenesis in vitro, Duan, Wei; Kearney, Michael; Gimble, J; Lopez, Mandi, 2017
Collagen and hydroxyapatite scaffolds stimulate distinct osteogenesis pathways, Lopez, Mandi; Duan, Wei; Haque, M; Kearney, Michael; Gimble, J, 2016
Feline multipotent stromal cells express major histocompatibility complex II and have endodermal transdifferentiation capacity, Duan, Wei; Dietrich, Marilyn; Lopez, Mandi, 2016
Gait changes vary among horses with naturally occurring osteoarthritis following intra-articular administration of autlogous platelet-rich plasma, Mirza, Mustajab; Bommala, Prakash; Richbourg, Heather; Rademacher, Nathalie; Kearney, Michael; Lopez, Mandi, 2016
Synthetic mRNA to dedifferentiate equine adult multipotent stromal cells, Lopez, Mandi; Jarazo, Javier; Bondioli, Ken; Gentry, G, 2016
Demineralized human bone matrix with syngeneic adult adipose-derived multipotent stromal cells accelerates spinal fusion, Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2015
Synthetic mRNA to dedifferentiate equine adult multipotent stromal cells, Lopez, Mandi; Jarazo, Javier; Fargason, Carmel; Bondioli, Ken; Gentry, G, 2015
Demineralized human bone matrix with syngeneic adult adipose-derived multipotent stromal cells accelerates spinal fusion, Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2015
Synthetic mRNA to dedifferentiate equine adult multipotent stromal cells, Lopez, Mandi; Jarazo, Javier; Fargason, Carmel; Bondioli, Ken, 2015
Morphological Analysis of the Saphenous Nerve in the Dog, McNulty, Margaret; Doyle, Tristan; Lopez, Mandi, 2015
Canine infra-patellar and subcutaneous adipose tissue derived multipotent stromal cells have similar in vitro behavior before and after cryopreservation, Lopez, Mandi; Duan, Wei; Zhang, Nan, 2015
Assessment of mandibular nerve block using bupivacaine in Yucatan miniature swine as a model for mandibular condylectomy and implant surgery, Lopez, Mandi; Bova, J; da Cunha, Anderson; Stout, Rhett; Bhumiratana, S; Eisig, S; Alfie, D; Vunjak-Novakovic, G, 2014
Canine infra-patellar and subcutaneous adipose tissue derived multipotent stromal cells have similar in vitro behavior before and after cryopreservation, Lopez, Mandi, 2014
Synthetic mRNA to dedifferentiate equine adult multipotent stromal cells, Lopez, Mandi; Jarazo, Javier; Fargason, Carmel; Bondioli, Ken; Gentry, G, 2014
Accelerated spinal fusion in nude rats with human adult adipose-derived multipotent stromal cells (ASCs) and syngeneic deminieralized bone matrix (DBM), Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2014
Carrier Scaffolds Direct Adult Equine Multipotent Stromal Cell Osteogenesis In Vivo, Lopez, Mandi; Kelly, Laura; Bommala, Prakash; Haque, Masudul; Duan, Wei; Xie, Lin; Hayes, Daniel, 2013
In vitro generation of mesenchymal neotissues by adipose and bone marrow derived adult equine multipotent stromal cells on collagen scaffolds, Lopez, Mandi; Xie, Lin; Zhang, Nan; Marsano, Anna; Vunjak-Novakovic, Gordana, 2013
Carrier Scaffolds Direct Adult Equine Multipotent Stromal Cell Osteogenesis In Vivo, Lopez, Mandi; Kelly, Laura; Bommala, Prakash; Haque, Masudul; Duan, Wei; Xie, Lin; Hayes, Daniel, 2013
Assessment of mandibular nerve block using bupivacaine in Yucatan miniature swine as a model for mandibular condylectomy and implant surgery, Lopez, Mandi; Bova, J; da Cunha, Anderson; Stout, Rhett; Bhumiratana, S; Eisig, S; Alfie, D; Vunjak-Novakovic, G, 2013
Assessment of mandibular nerve block using bupivacaine in Yucatan miniature swine as a model for mandibular condylectomy and implant surgery, Lopez, Mandi; Bova, J; da Cunha, Anderson; Stout, Rhett; Bhumiratana, S; Eisig, S; Alfie, D; Vunjak-Novakovic, G, 2013
Canine Intra-Articular Multipotent Stromal Cells (MSC) From Adipose Have the Highest in Vitro Expansion Rates, Multipotentiality, and MSC Immunophenotypes, Lopez, Mandi; Zhang, Nan; Dietrich, Marilyn, 2013
Radiographic, 2D and 3D CT Measures On Juvenile Canine Hips Indicate Osteoarthritis At Maturity, Lopez, Mandi; Andronescu, Anemone, 2013
Reconstruction of large animal bone defect with engineered autogenous anatomically-shaped bone graft, Lopez, Mandi; Bhumiratana, S; Yeager, K; Alfie, D; Eton, R; Bernhard, J; Bova, J; Shah, F; Gimble, J; Eisig, S; Vunjak-Novakovic, G, 2013
Adult multipotent stromal cells in normal and laminitic equine hooves, Lopez, Mandi; Feng, Dejiang; Pinto, Vanessa; Dessauer, Jenna; Simcoe, Raeanna, 2012
Binge alcohol consumption and primate bone, Lopez, Mandi; Les, Clifford; Bommala, Prakash; Pechey, Carola; Haque, Masudal; LeCapitaine, Nichole; Nelson, Steve; Bagby, Greg; Dufour, Jason; Molina, Patricia, 2012
Chronic alcohol consumption is associated with subtle alterations in femoral transcriptomic, compositional, and morphometric phenotype in male rhesus macaques, Lopez, Mandi; Les, Cliff; Bommala, Prakash; Carola, Pechey; Masudal, Haque; Nichole, LeCapitaine; Steve, Nelson; Bagby, Greg; Dufour, Jason; Molina, Patricia, 2012
In vitro expansion rates and multi-potentiality of canine adult intra-articular adipose, synovium, and ligament multipotent stromal cells, Lopez, Mandi; Zhang , Nan, 2012
In vitro tissue generation by adult equine multipotent stromal cells on collagen scaffolds, Lopez, Mandi; Xie, Lin; Gimble, Jeffrey; Vunjak-Novakovic, Gordana; Marsano, Anna; Zhang, Yanru, 2012
In vitro tissue generation by adult equine multipotent stromal cells on collagen scaffolds, Lopez, Mandi; Xie, Lin; Marsano, Anna; Zhang, Yanru; Vunjak-Novakovic, Gordana, 2012
Isolation and characterization of adult progenitor cells from healthy and laminitic hoof tissue, Lopez, Mandi; Pinto, Vanessa; Andrews, Frank; Gimble, Jeffrey, 2012
Isolation and characterization of fresh and revitalized multipotent cells from excised feline tissue, Lopez, Mandi; Zhang, Nan, 2012
Novel multipotent cell isolation technique for excised feline tissue, Lopez, Mandi; Zhang, Nan, 2012
Radiographic, 2D and 3D CT measurements to predict development of canine hip osteoarthritis at maturity, Lopez, Mandi; Andronescu, Anemone, 2012
Large animal study of TMJ condyle reconstruction using living tissue-engineered bone grafts, Lopez, Mandi; Bhumiratana, S; Yeager, K; Alfie, D; Eton, R; Bernhard, J; Bova, J; Shah, F; Gimble, J; Eisig, S; Vunjak-Novakovic, G, 2012
Tissue engineered autogenous anatomically-shape bone graft for temporomandibular joint condyle reconstruction: mid-point analysis, Lopez, Mandi; Bhumiratana, S; Yeager, K; Eton, R; Bernhard, J; Bova, J; Shah, F; Gimble, J; Eisig, S; Vunjak-Novakovic, G, 2012
A biomechanical comparison of three femoral fixation sites using the hamstring graft in canine cranial cruciate ligament reconstruction, Lopez, Mandi; Ho, L; Masahiro, S; Goodwin, L; Xie, L; Kearney, M, 2011
Adult equine mesencymal stromal cells on collagen scaffold for in vitro tissue generation, Lopez, Mandi; Xie, L; Gimble, J, 2011
Biomechanical algorithm to quantify forces from equine motion at the saddle position, Lopez, Mandi; Kaidapuram, N; Xie, L, 2011
Bioresorbable, nanocomposite coatings reduce microbial colonization of orthopaedic fixation devices, Lopez, Mandi, 2011
Characterization of stromal cells from equine laminae in vitro, Lopez, Mandi; Marigo, V; Andrews, Frank; Gimble, J, 2011
Chronic alcoholism inhibits adult stromal cell osteogeneisis in vivo by altering cytokine ratios, Lopez, Mandi; Bommala, P; Haque, M; Kelly, L; Spencer, N; Gimble, J; Bagby, G; Nelson, S, 2011
Chronic Alcoholism Inhibits Adults Stromal Cell Osteogenesis In Vivo Through Alterations in Cytokine Ratios, Lopez, Mandi; Bommala, P; Haque, M; Kelly, L; Spencer, N; Gimble, J; Bagby, G; Nelson, S, 2011
Equine Bone Regeneration with Stem Cell‐Scaffold Constructs, Lopez, Mandi, 2011
In vivo application of novel and commercially available bioabsorbabe implants for tibial fixation of cranial cruciate ligament reconstruction grafts, Lopez, Mandi; Bommala, P; Kelly, L; Zhang, N; Monroe, W, 2011
In vitro expansion rates and multipotential of adult canine stifle adipose, synovium and cranial cruciate ligament multipotent stromal cells, Lopez, Mandi; Zhang, N, 2011
Optimized loading and preculture conditions for adult adipose derived multipoint stromal cell osteogenesis on biocompatible scaffolds, Lopez, Mandi; Haque, M; Gimble, J, 2011
Breaking news on adult canine stem cells, Lopez, Mandi, 2010
Chronic Alcoholism Reduces Adult Stem Cell Function, Lopez, Mandi; Huff, N; Spencer, J; Bagby, G; Nelson, S; Gimble, J, 2010
In vitro comparison of adult canine bone marrow- and adipose derived stromal cell growth characteristics, Lopez, Mandi; Spencer, N; Chun, R; Vidal, M; Gimble, J, 2010
In vitro production of cortisol by equine fetal adrenal cells in response to ACTH and IL-1, Eilts, Bruce; Lyle, Sara; Hague, M; Lopez, Mandi; Beehan, David; Staempfli, Simon; Len, Jose; Paccamonti, Dale, 2010
Soft and hard keratins in the hooves of equine fetuses and adult horses, Lopez, Mandi; Bragulla, Hermann; Foster, A, 2010

Journal Article, Academic Journal:

Adult Multipotent Stromal Cell Cryopreservation: Pluses and Pitfalls, Duan, Wei; Lopez, Mandi; Hicok, Kevin, 2018, Veterinary Surgery , Volume: 47, Number: 1, Pages: 19-29
Joint stability after canine cranial cruciate ligament graft reconstruction varies among femoral fixation sites., Ho-Eckart, L; Seki, M; Luizza, L; Kearney, Michael; Lopez, Mandi, 2017, Veterinary surgery : VS , Volume: 46, Number: 2, Pages: 213-225
Gait Changes Vary among Horses with Naturally Occurring Osteoarthritis Following Intra-articular Administration of Autologous Platelet-Rich Plasma, Mirza, Mustajab; Bommalla, parakash; richbourg, heather; Rademacher, Nathalie; Kearney, Michael; Lopez, Mandi, 2016, Front Vet Sci , Volume: 3, Number: 29
Effects of Cryopreservation on Canine Multipotent Stromal Cells from Subcutaneous and Infrapatellar Adipose Tissue, Duan, W.; Lopez, Mandi, 2016, Stem Cell Rev , Pages: 1-12
Diagnosis, prevention, and management of canine hip dysplasia: a review, Lopez, Mandi; Schachner, Emma, 2015, Vet Med: Res Rep , Volume: 6, Pages: 181-192
Associations between early radiographic and computed tomographic measures and canine hip joint osteoarthritis at maturity, Andronescu, A.; Kelly, L.; Kearney, Michael; Lopez, Mandi, 2015, Am J Vet Res , Volume: 76, Number: 1, Pages: 19-27
In vitro and in vivo characterization of pentaerythritol triacrylate-co-trimethylolpropane nanocomposite scaffolds as potential bone augments and grafts., Chen, C; Garber, L; Smoak, M; Fargason, C; Scherr, T; Blackburn, C; Bacchus, S; Lopez, Mandi; Pojman, J; Del Piero, Fabio; Hayes, D, 2015, Tissue engineering. Part A , Volume: 21, Number: 1-2, Pages: 320-31
State of the art: Stem cells in equine regenerative medicine, Lopez, Mandi; Jazaro, Javier, 2014, Equine Vet J
Bench to bedside: it’s all about the model, Lopez, Mandi, 2014, Stem Cell Res & Therapy , Volume: 5, Number: 1, Pages: Article number 11
In vitro mesenchymal trilineage differentiation and extracellular matrix production by adipose and bone marrow derived adult equine multipotent stromal cells on a collagen scaffold, Lopez, Mandi; Xie, Lin; Marsano, Anna; Yanru, Zhang; Gordana, Vunjak-Novakovich; Nan, Zhang, 2013, Stem Cell Rev , Volume: 9, Number: 6, Pages: 858-872
Novel Anterior Cruciate Ligament Graft Fixation Device Reduces Slippage, Lopez, Mandi; Bommala, Prakash; Kelly, Laura; Zhang, Nan; Monroe, W.; Borne, A., 2013, Med Devices (Auckland) , Volume: 6, Pages: 59-68
Adult Stem Cell Therapies: A New Reality, Lopez, Mandi, 2013, NAVC Clinician’s Brief , Volume: 15, Pages: 69-71
Canine intra-articular multipotent stromal cells (MSC) from adipose tissue have the highest in vitro expansion rates, multipotentiality, and MSC immunophenotypes, Lopez, Mandi; Zhang, N; Dietrich, Marilyn, 2013, Vet Surg , Volume: 42, Number: 2, Pages: 137-146
In vitro comparison of adult canine bone marrow-derived and adipose tissue-derived stromal cell growth characteristics, Lopez, Mandi; Spencer, N; Chun, R; Vidal, M; Gimble, J, 2011, Veterinary Journal
Effects of Extracorporeal Shock Wave Therapy on Desmitis of the Accessory Ligament of the Deep Digital Flexor Tendon in the Horse, Burba, Daniel; Waguespack, R; Hubert, Jeremy; Vidal, Martin; Lomax, Larry; Lopez, Mandi, 2011, Veterinary Surgery

Book, Textbook Chapter:

Chapter 74 - Bone Biology and Fracture Healing, Lopez, Mandi; Markel, M, 2012, Publisher: Elsevier Science, Pages: 1025-1040
Adipogenic Differentiation of Adult Equine Mesenchymal Stromal Cells, Lopez, Mandi; Vidal, M, 2011, Publisher: Humana Press, Pages: 61-75
In vitro Adult Canine Adipose Tissue-Derived Stromal Cell Growth Characteristics, Lopez, Mandi; Spencer, Nakia, 2011, Publisher: Humana Press, Pages: 47-60
In Vitro Adult Rat Adipose Tissue-Derived Stromal Cell Isolation and Differentiation, Lopez, Mandi; Spencer, Nakia, 2011, Publisher: Humana Press, Pages: 37-46

Editorial:

Creative Technology Advances Tissue Preservation, Lopez, Mandi, 2017
Advances in Hip Dysplasia, Lopez, Mandi, 2012

Book, Textbook:

How to Eat Like a Dragon, Lopez, Mandi; Simmons, Lisa, 2015