Dr. Jennifer Sones
Associate Professor
Veterinary Clinical Sciences (VCS)
(225) 578-9500

Biography:
I am an Associate Professor of Theriogenology at LSU SVM. I received my BS (2004) and DVM (2008) from LSU and a PhD (2015) from Cornell University. I became a Diplomate of the American College of Theriogenologists in 2016.

Teaching Interests:
1. Equine, canine, and feline reproductive physiology
2. Equine pregnancy pathology
3. Reproductive Genomics and Molecular biology

Research Interests:
1. Comparative pregnancy physiology
2. Preeclampsia and fetal growth restriction
3. Equine placentitis

 Awards & Honors:
  • 2021 Dean's Teacher Merit Honor Roll
  • 2020 Forty Under 40
  • 2020 2020 Zoetis Research Award
  • 2020 APS Endocrinology & Metabolism New Investigator Award
  • 2020 Dean's Teacher Merit Honor Roll
  • 2019 Dean's Teacher Merit Honor Roll
  • 2018 Stephanie Watts Career Development Award
  • 2018 Dean's Teacher Merit Honor Roll
  • 2017 Theriogenology Foundation New Faculty Travel Grant
  • 2017 Dean's Teacher Merit Honor Roll
  • 2014 Best of American Heart Association Specialty Conferences Award
  • 2014 Best of American Heart Association Specialty Conferences Award
  • 2014 Invited speaker, NIH/NICHD Health Equity Seminar
  • 2014 New Investigator Travel Award
  • 2014 John and Joyce Wootton Fund Award for Graduate Education in Physiology
  • 2014 Dr. Caroline Coffey Memorial Travel Award
  • 2014 Data Diuresis Featured Abstract
  • 2013 3rd place oral presentation, 12th Annual Biological & Biomedical Sciences Symposium
  • 2012 DVM Graduate Research Assistantship
  • 2008 Equine Medicine & Surgery Proficiency Award
  • 2007 Scholarship Award
  • 2006 2nd place poster presentation
  • 2006 Equine Health Studies Program Scholarship Award
  • 2006 Havemeyer Foundation Fellowship
  • 2005 Equine Health Studies Program Scholarship Award
  • 2005 Merck Merial Summer Scholarship
  • 2003 1st place poster presentation
 Education:
  • PhD Cornell University
  • DVM Louisiana State University
  • BS Louisiana State University
 Grants:
  • Attenuation of maternal obesity in BPH/5 preeclamptic mice prevents cardiometabolic risk in female offspring, National Institutes of Health, Administrative Supplement for Research on Women’s Health in the IDeA States, $267,000.00
  • Defining the hepatic metabolic and inflammatory transcriptional markers of mid to late-gestation in BPH/5 and C57Bl/6 mice, VCS CORP, $4,000.00
  • Investigating the fecal microbiome of offspring in a sex-dependent manner in the BPH/5 preeclamptic-like model, VCS CORP, $4,000.00
  • Uteroplacental Kiss1/Kiss1r Protein Expression and Co-Expression of Estrogen Receptors in Preeclampsia: Longitudinal Studies using the BPH/5 Mouse, VCS CORP, $4,000.00
  • The Effects of Intrauterine Ceftiofur on the Equine Uterine Microbiome, 2020 Equine Health Studies Program, $5,000.00
  • Kisspeptins as pro-apoptotic mediators during equine endometrial cup demise, Theriogenology Foundation, $5,000.00
  • Metabolic Basis of Disease, National Institutes of Health COBRE, $666,000.00
  • Characterization of the placental microbiome in the obese preeclamptic-like BPH/5 mouse, 2019 SVM CORP, $10,000.00
  • Benefits of progesterone: missing in action during preeclampsia, American Heart Association, $231,000.00
  • Linking fecal microbiome and hypertension of offspring in a sex-dependent manner in the BPH/5 preeclamptic-like model, VCS CORP, $4,000.00
  • Open Access Author Fund, LSU Libraries, $1,500.00
  • Open Access Author Fund, LSU Libraries, $1,500.00
  • Regulation of BAT Function and Offspring Metabolism via Maternal-Fetal Crosstalk, Pennington Biomedical Research Center, Nutrition Obesity Research Center, $65,288.00
  • The preeclampsia-like BPH/5 mouse: A murine model of preeclampsia induced liver dysfunction?, VCS CORP, $4,000.00
  • Comparison of the placental microbiome in the obese preeclamptic-like BPH/5 mouse to the vaginal, oral, and fecal microbiomes, VCS CORP, $4,000.00
  • Effects of kisspeptin-10 on in vitro migration and secretory activity of invasive equine chorionic girdle trophoblast cells, VCS CORP, $4,000.00
  • Reducing dyslipidemia: the use of statins to improve placentation in the preeclampsia-like BPH/5 mouse, VCS CORP, $5,000.00
  • Hormonal induction of early cyclicity in seasonally anovulatory equids, 2018 ACRES, $47,471.00
  • The contribution of distinct cell populations within maternal adipose tissue on complement levels inthe preeclamptic-like BPH/5 mouse., 2018 SVM CORP, $9,200.00
  • Metagenetic characterization of the resident uterine microbiome in the horse., Equine Health Studies Program, $12,000.00
  • Metabolic characterization of the BPH/5 mouse model of preeclampsia, VCS Corp, $6,000.00
  • The role of maternal adiposity in complement deposition at the maternal-fetal interface during early pregnancy in the preeclamptic-like BPH/5 mouse., SVM Corp, $10,000.00
  • The role of maternal adipose tissue in the preeclamptic-like BPH/5 mouse., Louisiana Biomedical Collaborative Research Program, $50,000.00
  • Measurement of serum amyloid A levels in clinical cases of equine placentitis., Equine Health Studies Program, LSU SVM, $6,000.00
  • Characterization of steroid hormone responsive genes in the equine endometrium during induced aluteal cycles, VCS CORP, $4,000.00
  • Developmental characteristics of in vivo equine embryos produced during induced aluteal cycles, Charles V. Cusimano EHSP grant, $6,000.00
  • Antiluteogenic Treatment of Hemorrhagic Anovulatory Follicles Induced with Flunixin Meglumine, Equine Health Studies Program, $6,000.00
 Publications:
Journal Article, Academic Journal:
  • Genotypic analysis of the female BPH/5 mouse, a model of superimposed preeclampsia, Sones, Jennifer; Yarborough, C.; O'Besso, V.; Lemenze, A.; Douglas, N., 2021, PloS one , Volume: 16, Number: 7, Pages: e0253453
  • Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice, Ghosh, S.; Park, C.; Lee, J.; Lee, N.; Zhang, R.; Huesing, C.; Reijnders, D.; Sones, Jennifer; Münzberg, H.; Redman, L.; Chang, J., 2021, BMC genomics , Volume: 22, Number: 1, Pages: 500-021-07825-6
  • Renal failure in a pregnant mare: A case report, de Aguiar, Luis; Gomes, Viviane; Paul, Linda; Andrews, Frank; Chaffin, Morgan; Sones, Jennifer, 2020, Equine Veterinary Education
  • Theriogenology Question of the Month "Subinvolution of placental sites in a dog", Mak, C.; Sasaki, E.; Bauer, Rudy; H. de Aguiar, L.; Gomes, Viviane; Sones, Jennifer; Pinto, Carlos, 2020, Journal of the American Veterinary Medical Association , Volume: 257, Number: 11, Pages: 1129-1132
  • Equine focal mucopurulent placentitis associated with Stenotrophomonas maltophilia, Gomes, Viviane; Del Piero, Fabio; Langohr, Ingeborg; Aguiar, Luis; Anderson, Amanda; Sones, Jennifer; Pinto, Carlos, 2020, Equine Veterinary Education , Volume: 33, Number: 9, Pages: e292-e297
  • Maternal microbiome and the hypertensive disorder of pregnancy, preeclampsia, Beckers, Kalie; Sones, Jennifer, 2019, American journal of physiology.Heart and circulatory physiology
  • Role for the mammalian female reproductive tract microbiome in pregnancy outcomes, Heil, B.; Paccamonti, Dale; Sones, Jennifer, 2019, Physiological genomics , Volume: 51, Number: 8, Pages: 390-399
  • Conditional loss of ERK1 and ERK2 results in abnormal placentation and delayed parturition in the mouse, Brown, J.; Sones, Jennifer; Angulo, C.; Abbott, K.; Miller, A.; Boehm, U.; Roberson, M., 2019, Scientific reports , Volume: 9, Number: 1, Pages: 9641-019-45997-0
  • Dyslipidemia and the role of the adipose tissue in early pregnancy in the BPH/5 mouse model for preeclampsia, Reijnders, D.; Olson, K.; Liu, C.; Beckers, K.; Ghosh, S.; Redman, L.; Sones, Jennifer, 2019, American journal of physiology.Regulatory, integrative and comparative physiology
  • Embryos and endometrium collected on day 8 of induced aluteal cycles in the mare exhibit altered gene expression, Leisinger, Chelsey; Klein, Claudia; Markle, Mariah; Premanandan, Christopher; Sones, Jennifer; Pinto, Carlos; Paccamonti, Dale, 2019, Theriogenology , Volume: 128, Pages: 81-90
  • Effects of flunixin meglumine on postponement of ovulation in mares, Donnelly, C.; Sones, Jennifer; Dockweiler, J.; Norberg, L.; Norberg, L.; Cheong, S.; Gilbert, R., 2019, American Journal of Veterinary Research , Volume: 80, Number: 3, Pages: 306-310
  • Efficacy and outcome of foaling augmented with oxytocin using mammary calcium and pH criteria to guide the timing of augmentation, Cheong, S.; Herrera, J.; Dockweiler, J.; Donnelly, C.; Sones, Jennifer; Ellerbrock, R.; Lawlis, S.; Gilbert, R.; Diel de Amorim, M., 2019, Animal Reproduction Science , Volume: 202, Pages: 87-95
  • Obesity "complements" preeclampsia, Olson, K.; Redman, L.; Sones, Jennifer, 2019, Physiological genomics , Volume: 51, Number: 3, Pages: 73-76
  • Concentrations of sulfadiazine and trimethoprim in blood and endometrium of mares following administration of an oral suspension, Davolli, Gabriel; Beavers, Kelli; Medina, Victor ; Sones, Jennifer; Pinto, Carlos; Paccamonti, Dale; Causey, Robert, 2018, Journal of Equine Veterinary Science , Volume: 67, Pages: 27-30
  • Celecoxib restores angiogenic factor expression at the maternal-fetal interface in the BPH/5 mouse model of preeclampsia, Reijnders, D.; Liu, C.; Xu, X.; Zhao, A.; Olson, K.; Butler, S.; Douglas, N.; Sones, Jennifer, 2018, Physiological genomics , Volume: 50, Number: 5, Pages: 385-392
  • Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia, Sones, Jennifer; Merriam, A.; Seffens, A.; Brown-Grant, D.; Butler, S.; Zhao, A.; Xu, X.; Shawber, C.; Grenier, J.; Douglas, N., 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • Sex- and age-specific impact of ERK loss within the pituitary gonadotrope in mice, Brown, J.; Xie, J.; Enriquez, M.; Sones, Jennifer; Angulo, C.; Boehm, U.; Miller, A.; Toufaily, C.; Wang, Y.; Bernard, D.; Roberson, M., 2018, Endocrinology , Volume: 159, Number: 3, Pages: 1264-76
  • The decidua of preeclamptic-like BPH/5 mice exhibits an exaggerated inflammatory response during early pregnancy, Heyward, C.; Sones, Jennifer; Lob, H.; Yuen, L.; Abbott, K.; Huang, W.; Begun, Z.; Butler, S.; August, A.; Leifer, C.; Davisson, R., 2017, Journal of reproductive immunology , Volume: 120, Pages: 27-33
  • The decidua of preeclamptic-like BPH/5 mice exhibits an exaggerated inflammatory response during early pregnancy., Heyward, C; Sones, Jennifer; Lob, H; Yuen, L; Abbott, K; Huang, Weishan; Begun, Z; Butler, S; August, A; Leifer, C; Davisson, R, 2017, Journal of reproductive immunology , Volume: 120, Pages: 27-33
  • Adverse Metabolic Phenotype of Female Offspring Exposed to Preeclampsia in utero: A Characterization of the BPH/5 Mouse in Postnatal Life, Sutton, E.; Lob, H.; Song, J.; Xia, Y.; Butler, S.; Liu, C.; Redman, L.; Sones, Jennifer, 2017, American journal of physiology.Regulatory, integrative and comparative physiology , Pages: ajpregu.00512.2016
  • Preeclampsia, of mice and women, Sones, Jennifer; Davisson, R., 2016, Physiological genomics , Volume: 48, Number: 8, Pages: 565-572
  • Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model, Sones, Jennifer; Cha, J.; Woods, A.; Bartos, A.; Heyward, C.; Lob, H.; Isroff, C.; Butler, S.; Shapiro, S.; Dey, S.; Davisson, R., 2016, JCI insight , Volume: 1, Number: 3, Pages: e75351
  • Role of decidual natural killer cells, interleukin-15, and interferon-gamma in placental development and preeclampsia, Sones, Jennifer; Lob, H.; Isroff, C.; Davisson, R., 2014, American journal of physiology.Regulatory, integrative and comparative physiology , Volume: 307, Number: 5, Pages: R490-2
  • Novel expression of EGFL7 in placental trophoblast and endothelial cells and its implication in preeclampsia, Lacko, L.; Massimiani, M.; Sones, Jennifer; Hurtado, R.; Salvi, S.; Ferrazzani, S.; Davisson, R.; Campagnolo, L.; Stuhlmann, H., 2014, Mechanisms of development , Volume: 133, Pages: 163-176
  • Interleukin-15 contributes to decidual natural killer cell loss via interferon-γ during early pregnancy in the pre-eclamptic BPH/5 mouse model (1083.1), Sones, Jennifer; Lob, Heinrich; Isroff, Catherine; Song, Jiunn; Williamson, Emilie; Davisson, Robin, 2014, The FASEB Journal , Volume: 28, Number: 1 Supplement
  • Distal-less 3 haploinsufficiency results in elevated placental oxidative stress and altered fetal growth kinetics in the mouse, Clark, P.; Brown, J.; Li, S.; Woods, A.; Han, L.; Sones, Jennifer; Preston, R.; Southard, T.; Davisson, R.; Roberson, M., 2012, Placenta , Volume: 33, Number: 10, Pages: 830-838
Magazine/Trade Publication:
  • Managing Placentitis: A Leading Cause of Reproductive Loss, Sones, Jennifer, 2020
  • Maintenance of pregnancy in mares without a source of endogenous progesterone using Altren, Davolli, Gabriel; Sones, Jennifer; Paccamonti, Dale, 2018
  • Seasonality of Reproduction in Horses, Oberhaus, Erin; Sones, Jennifer, 2016
  • Breeding success after a racing career, Sones, Jennifer, 2016
Journal Article, Professional Journal:
  • Preeclampsia: Basic Researcher's Perspective, Davisson, Robin; Sones, Jennifer, 2015, Endocrine News: Tri-Point Series , Pages: 32-34
Scientific Abstract:
  • Reduction of maternal adiposity attenuates leptin expression during pregnancy in the preeclamptic-like BPH/5 mouse, Olson, Kelsey; Reijnders, Dorien; Liu, Chin-chi; Gomes, Viviane; Redman, Leanne; Sones, Jennifer, 2019
  • Day 8 Embryos and Endometrium From Aluteal Cycles in Mares Exhibit Differential Gene Expression, Leisinger, Chelsey; Klein, Claudia; Markle, Mariah; Premanandan, Christopher; Sones, Jennifer; Pinto, Carlos; Paccamonti, Dale, 2018
  • Calorie Restriction In The Preeclamptic-like BPH/5 Mouse Reduces Adipose Tissue Gene Expression of Preeclampsia-related Inflammatory Genes, Reijnders, Dorien; Olson, Kelsey; Redman, Leanne; Sones, Jennifer, 2018
  • Inflammatory Reproductive White Adipose Tissue Characterizes The Obese Preeclamptic-like BPH/5 Mouse prior to Pregnancy, Olson, Kelsey; Reijnders, Dorien; Douglas, Nataki; Redman, Leanne; Sones, Jennifer, 2018
  • Concentrations of sulfadiazine and trimethoprim in blood and endometrium of mares following administration of an oral suspension, Davolli, Gabriel; Beavers, Kelli; Medina, Victor; Sones, Jennifer; Pinto, Carlos; Paccamonti, Dale; Causey, Robert, 2017
  • Metagenomic analysis of the equine placental microbiome, Xia, Yun Wei; Cornelius, A; Donnelly, Callum; Bicalho, R; Cheong, Soon Hon; Sones, Jennifer, 2017
  • Inflammatory Mediators during the Pre-implantation Period Play a Key Role in the Pathogenesis of Preeclampsia in the Spontaneous Preeclamptic-like BPH/5 Mouse, Sones, Jennifer; Merriam, Audrey; Grenier, Jen; Douglas, Nataki; Davisson, Robin, 2017
  • Pre-Conception Leptin Resistance Characterizes the BPH/5 Mouse Model of Preeclampsia, Sutton, Elizabeth; Lob, Heinrich; Liu, Chin-Chi; Redman, Leanne; Davisson, Robin; Sones, Jennifer, 2017
  • Alterations in the complement pathway in a mouse model of preeclampsia, Merriam, Audrey; Xu, Xinjing; Davisson, Robin; Sones, Jennifer; Douglas, Nataki, 2017
  • Artificial Synchronization of Ovarian Hormones in Early Pregnancy Improves Adverse Pregnancy Outcomes Associated with Preeclampsia in the BPH/5 Mouse Model, Sones, Jennifer; Woods, Ashley; Cha, Jeeyeon; Dey, Sudhansu; Davisson, Robin, 2016
  • Loss of ERK1/2 Signaling in Cells Expressing the GnRH Receptor Causes Prolonged Gestation, Dystocia, and Fetal Death, Brown, Jessica; Sones, Jennifer; Boehm, Ulrich; Roberson, Mark, 2016
  • MicroRNAs Target Decidual Angiogenic Factors During Early Pregnancy in BPH/5, a Spontaneous Mouse Model of Preeclampsia, Xia, June; Baxter, Samuel; Grenier, Jen; Davisson, Robin; Sones, Jennifer, 2016
  • Normalization of Uterine Interleukin (IL)-15 in the BPH/5 Preeclamptic Mouse Improves Decidual Natural Killer Cell Activation at the Maternal-Fetal Interface, Sones, Jennifer; Heyward, Christa; Lessard, Dominique; Butler, Scott; Lob, Heinrich; Davisson, Robin, 2015
  • Cox2 Inhibition in Early Pregnancy Improves Adverse Outcomes in the BPH/5 Mouse Model of Preeclampsia (PE), Sones, Jennifer; Butler, Scott; Shapiro, Stephanie; Cha, Jeeyeon; Dey, Sudhansu; Davisson, Robin, 2015
  • BPH/5 Pre-eclamptic Mice Have Increased Uterine Interleukin (IL)-15 And This Is Associated with Decidual Natural Killer (dNK) Cell Loss At The Maternal-Fetal Interface Early In Pregnancy, Sones, Jennifer; Lob, Heinrich; Isroff, Catherine; Song, Jiunn; Williamson, Emilie; Davisson, Robin, 2014
  • Cox2 Inhibition During Decidualization Improves Fetal Growth Restriction In The BPH/5 Mouse Model Of Preeclampsia, Sones, Jennifer; Butler, Scott; Isroff, Catherine; Cha, Jeeyeon; Dey, Sudhansu; Davisson, Robin, 2014
  • Evidence For Increased Autophagy In Fetoplacental Units Of Bph/5, A Mouse Model Of Pre-eclampsia (PE), Valbuena-Diez, Ana; Sones, Jennifer; Butler, Scott; Patel, Unisha; Davisson, Robin, 2014
  • Cox2 Signaling During the Peri-implantation Period Plays an Important Role in Fetoplacental Heath in a Mouse Model of Preeclampsia, BPH/5, Sones, Jennifer; Cha, Jeeyeon; Isroff, Catherine; Dey, Sudhansu; Davisson, Robin, 2013
  • Ovarian Hormone Signaling Defects are Associated with Asynchronous Peri-implantation Events in a Mouse Model of Preeclampsia, BPH/5, Sones, Jennifer; Zhou, Y.; Woods, A.; Isroff, C.; Knudsen, M.; Davisson, R., 2013
  • Decreased expression of Gcm1 and its downstream targets Syncytin A and B is associated with severity of feto-placental phenotypes in the BPH/5 model of preeclampsia (PE), Sones, Jennifer; Zhou, Yi; Woods, Ashley; Davisson, Robin, 2012
  • Thrombospondin-2 may exert its effects on fetoplacental development in the BPH/5 mouse model of preeclampsia (PE) through CD36 and CD47 receptors, Zhou, Yi; Sones, Jennifer; Woods, Ashley; Davisson, Robin, 2012
  • Investigation of the role of integrin α2 subunit in equine trophoblast attachment, Sones, Jennifer; Miller, Donald; de Mestre, Amanda; DeCarlo, Christine; Harman, Rebecca; Antczak, Douglas, 2010