Dr. Fabio Del Piero
Professor
Pathobiological Sciences (PBS)

Biography:
Fabio Del Piero graduated from University of Milan Italy where he spent additional time studying in the Department of Anatomic and Avian Pathology. Following a period as a veterinary practitioner and food inspector in Italy he moved abroad in 1991. He spent two years in the British islands studying pathology and infectious diseases, in particular with the department of infectious diseases of The Animal Health Trust in Newmarket, England. In 1996 he completed a residency program in anatomic pathology in the Department of Pathology of the College of Veterinary Medicine of Cornell University ad Ithaca, New York. Then he spend 2 years as postdoctoral associate in the Cornell University New York State Diagnostic laboratory as a pathologist supervising the immunohistochemistry laboratory. In 1997 he became a Diplomate of American College of Veterinary Pathologists and was elected an honorary member of Phi-Zeta, the Veterinary Honor Society in the United States. He is a member of three chapters, Cornell University (alfa), PennVet (beta), LSU (tau). Following a brief period as a faculty in veterinary pathology in Italy, he was faculty in the Department of Pathobiology of the School of Veterinary Medicine of University of Pennsylvania from 1999 until 2011, with an affiliate appointment in the Department of Clinical Studies-New Bolton Center. His appointment included diagnostic, teaching and research activity for both University of Pennsylvania and the Pennsylvania Animal Diagnostic Laboratories (PADLS). In January 2012 he joined the faculty at Louisiana State University as full professor of pathology tenure track and chief of the molecular pathology laboratory. He obtained his PhD in the pathogenesis of zoonotic arboviruses in 2003. Research activity includes the study of the pathogenesis of infectious diseases, reproductive pathology with an emphasis on fetal and neonatal pathology, neuropathology and comparative pathology. Recent studies have been focusing on zoonotic viral and bacterial agents such as West Nile virus, Eastern equine encephalitis virus, Zika virus, Herpesviruses, Rickettsial diseases, and Yersinia pestis and Klebsiella pneumoniae pneumonia models. He is international renowned for his expertise in equine pathology and has more than 25 years expertise in this field. He is author and coauthor of approximately 110 peer reviewed publication, 90 abstracts, 3 books, several book chapters and an atlas of equine pathology. In 2003 he received the Ljudevit Jurak Award for his studies and teaching in the field of comparative pathology. He received more than 100 invitations as a speaker at meetings and various national and international institutions. He is member of the board of directors and Vice-president Senior of the Davis-Thompson foundation for the study, practice and teaching of comparative pathology and veterinary medicine and overseas member of the British veterinary research club. He served in several ACVP committees and editorial board and he was the program chair of the 2009 ACVP meeting.

Teaching Interests:
Comparative Pathology Infectious Diseases Diagnostic Pathology Molecular Pathology

Research Interests:
Comparative Pathology Infectious diseases Diagnostic Pathology Molecular Pathology

 Awards & Honors:
  • 2016 Dean's Teacher Merit Honor Roll
  • 2015 Dean's Teacher Merit Honor Roll
  • 2014 Lifetime Honorary Member of The Italian Association of Veterinary Pathologists
  • 2014 Lifetime Honorary Member of The Italian Society of Veterinary Sciences
  • 2014 Dean's Teacher Merit Honor Roll
  • 2009 Barbara Jean Thompson Service Award
  • 2003 Ljudevit Jurak Comparative Pathology Award
  • 2000 The Outstanding Young Person
 Education:
  • PhD University of Turin
  • DVM University of Milan
 Grants:
  • Veterinary Services for the Louisiana Alligator Industry, Louisiana Department of Wildlife and Fisheries, $89,280.00
  • Histologic Changes to the Muscular Portion of the Hind Suspensory Ligament of Horses as a Result of Neurectomy of the Deep Branch of the Lateral Plantar Nerve., Charles V. Cusimano EHSP , $1,340.00
  • Identification of a genetic predisposition for horses to develop Equine Protozoal Myeloencephalitis (EPM) and associated gene dysregulation , Virginia Tech, Equine Research Internal Funding program, $9,000.00
  • Equine Protozoal Myeloencephalitis (EPM): Identifying the immune response and the role of infection , Virginia Maryland Regional College of Veterinary Medicine Internal Grant, $19,998.00
 Publications:
Book, Textbook Chapter:
  • Equine neuropathology, Del Piero, Fabio, 2015, Publisher:
  • Diseases of the Eye and Ear, Langohr, Ingeborg, 2014, Publisher: Wiley and Blackwell, Pages: 451-470
Journal Article, Academic Journal:
  • Zebra-borne neurotropic equid herpesvirus 1 meningoencephalitis in a Thomson's gazelle ( Eudorcas thomsonii)., Sakaguchi, K; Kim, K; Langohr, Ingeborg; Wise, A; Maes, R; Pirie, G; Yanai, T; Haridy, M; Gaschen, Lorrie; Del Piero, Fabio, 2017, Journal of Veterinary Diagnostic Investigation , Volume: 29, Number: 4, Pages: 548–556
  • Pathology in Practice. Granulosa cell tumor in a Mongolian gerbil., Malbrue, R; Arsuaga, C; Jay, A; Smith, N; Dehghanpir, S; Kawabata, A; Grasperge, Britton; Del Piero, Fabio, 2017, Journal of the American Veterinary Medical Association , Volume: 250, Number: 9, Pages: 989-992
  • Intramuscular Immunization of Mice with the Live-Attenuated Herpes Simplex Virus Type-1(HSV-1) Vaccine Strain VC2 Expressing the Equine Herpesvirus-1 (EHV-1) Glycoprotein D (gD) Generates Anti-EHV-1 Immune Responses in Mice, Liu, Shiliang; Stanfield, Brent; Chouljenko, Vladimir; Naidu, Shan; Langohr, Ingeborg; Del Piero, Fabio; Ferracone, Jacqueline; Roy, Alma; Kousoulas, Konstantin, 2017, Journal of Virology , Pages: JVI.02445-16
  • Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model, Kawiecki, Anna; Mayton, E.; Dutuze, M.; Goupil, Brad; Langohr, Ingeborg; Del Piero, Fabio; Christofferson, Rebecca, 2017, Virology Journal , Volume: 14, Number: 1
  • Equine Arteritis Virus has Specific Tropism for Stromal Cells and CD8<sup>+</sup> T and CD21<sup>+</sup> B Lymphocytes but not Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract., Carossino, M; Loynachan, A; Canisso, I; Cook, R; Campos, J; Nam, B; Go, Y; Squires, E; Swerczek, T; Del Piero, Fabio; Bailey, E; Timoney, P, 2017, Journal of virology
  • Salmonella Enterica Serovar Pomona Infection in Farmed Juvenile American Alligators ( Alligator Mississippiensis)., Sakaguchi, K; Nevarez, Javier; Del Piero, Fabio, 2017, Veterinary pathology , Volume: 54, Number: 2, Pages: 316-319
  • Detection of equine arteritis virus by two chromogenic RNA in situ hybridization assays (conventional and RNAscope(®)) and assessment of their performance in tissues from aborted equine fetuses., Carossino, M; Loynachan, A; James MacLachlan, N; Drew, C; Shuck, K; Timoney, P; Del Piero, Fabio; Balasuriya, U, 2016, Archives of virology , Volume: 161, Number: 11, Pages: 3125-36
  • Cardiomyopathy in a harris hawk (Parabuteo unicinctus), Nevarez, Javier; Brandao, Joao; Beaufrere, Hugues ; Reynolds, Caryn; Johnson, Jimmy; Gaschen, Lorrie; Del Piero, Fabio; Tully, Thomas, 2016, Journal of the Amercian Veterinary Medical Association , Volume: 249 , Number: 2, Pages: 221-227
  • Metastatic leiomyosarcoma causing ataxia in a horse, Kawabata, A; Del Piero, Fabio; Caserto, B; Langohr, Ingeborg, 2016, Journal of Equine Veterinary Science , Volume: 43, Pages: 23-7
  • NLRP12 modulates host defense through IL-17A-CXCL1 axis., Cai, S; Batra, Sanjay; Del Piero, Fabio; Jeyaseelan, Samithamby, 2016, Mucosal immunology , Volume: 9, Pages: 718-29
  • Nonselective Persistence of a Rickettsia conorii Extrachromosomal Plasmid during Mammalian Infection., Riley, S; Fish, A; Garza, D; Banajee, K; Harris, E; Del Piero, Fabio; Martinez, Juan, 2016, Infection and immunity , Volume: 84, Number: 3, Pages: 790-7
  • Evaluation of the genes encoding CD39/NTPDase-1 and CD39L1/NTPDase-2 in horses with and without abnormal hemorrhage and in horses with pathologic evidence of exercise-induced pulmonary hemorrhage., Boudreaux, M; Koehler, J; Habecker, P; Del Piero, Fabio, 2015, Veterinary clinical pathology , Volume: 44, Number: 4, Pages: 617-25
  • Failure of a heterologous recombinant Sca5/OmpB protein-based vaccine to elicit effective protective immunity against Rickettsia rickettsii infections in C3H/HeN mice., Riley, S; Cardwell, M; Chan, Y; Pruneau, L; Del Piero, Fabio; Martinez, Juan, 2015, Pathogens and disease , Volume: 73, Number: 9, Pages: ftv101
  • Evaluation of bone regeneration potential of dental follicle stem cells for treatment of craniofacial defects., Rezai-Rad, M; Bova, J; Orooji, M; Pepping, J; Qureshi, A; Del Piero, Fabio; Hayes, D; Yao, Shaomian, 2015, Cytotherapy , Volume: 17, Number: 11, Pages: 1572-81
  • Co-feeding intra- and interspecific transmission of an emerging insect-borne rickettsial pathogen., Brown, L; Christofferson, Rebecca; Banajee, K; Del Piero, Fabio; Foil, L; Macaluso, Kevin, 2015, Molecular ecology
  • First report of <i>Cylicospirura felineus</i> in a feral domestic shorthair cat in North America., Crossland, N; Hanks, C; Ferguson, J; Kent, M; Sanders, J; Del Piero, Fabio, 2015, JFMS open reports , Volume: 1, Number: 2, Pages: 2055116915593964
  • Pathology in Practice: Mediastinal thyroid follicular carcinoma and adrenal carcinoma, Gaunt, Stephen; Del Piero, Fabio; Leissinger, Mary; Kawabata, Atsushi; Dedeaux, Andrea, 2015, J American Veterinary Medical Association , Volume: 246, Pages: 303-305
  • In vitro and in vivo characterization of pentaerythritol triacrylate-co-trimethylolpropane nanocomposite scaffolds as potential bone augments and grafts., Chen, C; Garber, L; Smoak, M; Fargason, C; Scherr, T; Blackburn, C; Bacchus, S; Lopez, Mandi; Pojman, J; Del Piero, Fabio; Hayes, D, 2015, Tissue engineering. Part A , Volume: 21, Number: 1-2, Pages: 320-31
  • Photoactivated miR-148b-nanoparticle conjugates improve closure of critical size mouse calvarial defects., Qureshi, A; Doyle, A; Chen, C; Coulon, D; Dasa, V; Del Piero, Fabio; Levi, B; Monroe, W; Gimble, J; Hayes, D, 2015, Acta biomaterialia , Volume: 12, Pages: 166-73
  • miR-196a expression in human and canine osteosarcomas: A comparative study., Pazzaglia, L; Leonardi, L; Conti, A; Novello, C; Quattrini, I; Montanini, L; Roperto, F; Del Piero, Fabio; Di Guardo, G; Piro, F; Picci, P; Benassi, M, 2014, Research in veterinary science
  • Pathology in practice. Hepatic hematoma with subcapsular rupture in a dog., Maxwell, E; Del Piero, Fabio; Kulshreshtha, V; Saile, Katrin, 2014, Journal of the American Veterinary Medical Association , Volume: 245, Number: 12, Pages: 1343-5
  • Characterization of IgE-mediated cutaneous immediate and late-phase reactions in non-allergic horses. , Woodward, Michelle; Merchant, Sandra; Andrews, Frank; Kearney, Michael; Del Piero, Fabio; Woodward, MIchelle, 2014, Veterinary Dermatology , Volume: 24, Number: 3, Pages: 305
  • Role of TLR4 in Lipopolysaccharide-induced Acute Kidney Injury: Protection by Blueberry, Nair, Anand; Masson, Gustavo; Francis, Joseph; Ebenezer, Philip; Del Piero, Fabio, 2014, Free Radical Biology & Medicine , Volume: 71C, Pages: 16-25
  • Role of TLR4 in lipopolysaccharide-induced acute kidney injury: protection by blueberry., Nair, A; Masson, G; Ebenezer, P; Del Piero, Fabio; Francis, Joseph, 2014, Free radical biology & medicine , Volume: 71, Pages: 16-25
  • Role of TLR4 in lipopolysaccharide-induced acute kidney injury: Protection by blueberry., Nair, A; Masson, G; Ebenezer, P; Del Piero, Fabio; Francis, Joseph, 2014, Free radical biology & medicine , Volume: 71C, Pages: 16-25
  • Equine herpesvirus 1 (EHV-1) nucleotide polymorphism determination using formalin fixed tissues in EHV-1 induced abortions and myelopathies with real-time PCR and pyrosequencing., Del Piero, Fabio; Tewari, Deepanker; Cieply, S; Feria, W; Acland, Helen, 2013, Journal of Virological Methods
  • Distribution of eastern equine encephalomyelitis viral protein and nucleic acid within central nervous tissue lesions in white-tailed deer (Odocoileus virginianus)., Kiupel, M; Fitzgerald, S; Pennick, K; Cooley, T; O'Brien, D; Bolin, S; Maes, R; Del Piero, Fabio, 2013, Veterinary pathology , Volume: 50, Number: 6, Pages: 1058-62
  • Equine herpesvirus 1 (EHV-1) nucleotide polymorphism determination using formalin fixed tissues in EHV-1 induced abortions and myelopathies with real-time PCR and pyrosequencing., Tewari, D; Del Piero, Fabio; Cieply, S; Feria, W; Acland, H, 2013, Journal of virological methods , Volume: 193, Number: 2, Pages: 371-3
  • Chronic dermatitis caused by Lactobacillus jensenii infection in a blue and gold macaw (Ara ararauna)., Brandão, J; Wong, C; Kurotaki, T; Johnson, Jill; Mitchell, M; Roy, Alma; Pucheu-Haston, Cherie; Del Piero, Fabio; Tully, Thomas, 2013, Journal of the American Veterinary Medical Association , Volume: 243, Number: 7, Pages: 1030-4
  • Esophageal adenocarcinoma in a 53-year-old mata mata turtle (Chelus fimbriatus)., Lombardini, E; Desoutter, A; Montali, R; Del Piero, Fabio, 2013, Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians , Volume: 44, Number: 3, Pages: 773-6
  • Polyomavirus-associated nephritis in 2 horses., Jennings, S; Wise, A; Nickeleit, V; Maes, R; Cianciolo, R; Del Piero, Fabio; Law, J; Kim, Y; McCalla, A; Breuhaus, B; Roberts, M; Linder, K, 2013, Veterinary pathology , Volume: 50, Number: 5, Pages: 769-74
  • Hepatoencephalopathy syndrome due to Cassia occidentalis (Leguminosae, Caesalpinioideae) seed ingestion in horses., Oliveira-Filho, J; Cagnini, D; Badial, P; Pessoa, M; Del Piero, Fabio; Borges, A, 2013, Equine veterinary journal , Volume: 45, Number: 2, Pages: 240-4
  • Atypical cerebral listeriosis associated with Listeria innocua in a beef bull., Rocha, P; Dalmasso, A; Grattarola, C; Casalone, C; Del Piero, Fabio; Bottero, M; Capucchio, M, 2013, Research in veterinary science , Volume: 94, Number: 1, Pages: 111-4
  • Mycobacterium DNA detection in liver and skin of a horse with generalized sarcoidosis., Oliveira-Filho, J; Monteiro, L; Delfiol, D; Sequeira, J; Amorim, R; Fabris, V; Del Piero, Fabio; Borges, A, 2012, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc , Volume: 24, Number: 3, Pages: 596-600
  • Strain impact on equine herpesvirus type 1 (EHV-1) abortion models: viral loads in fetal and placental tissues and foals., Gardiner, D; Lunn, D; Goehring, L; Chiang, Y; Cook, C; Osterrieder, N; McCue, P; Del Piero, Fabio; Hussey, S; Hussey, G, 2012, Vaccine , Volume: 30, Number: 46, Pages: 6564-72
  • Ocular melanoma and mammary mucinous carcinoma in an African lion., Cagnini, D; Salgado, B; Linardi, J; Grandi, F; Rocha, R; Rocha, N; Teixeira, C; Del Piero, Fabio; Sequeira, J, 2012, BMC veterinary research , Volume: 8, Pages: 176
Scientific Abstract:
  • Vaccination of American alligators (Alligator mississippiensis) with a killed West Nile virus vaccine: implications for interpretation of serology and tissue RT-PCR, Roy, Alma; Higbie, Christine ; Nevarez, Javier; Del Piero, Fabio, 2017
  • Demineralized human bone matrix with syngeneic adult adipose-derived multipotent stromal cells accelerates spinal fusion, Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2015
  • Demineralized human bone matrix with syngeneic adult adipose-derived multipotent stromal cells accelerates spinal fusion, Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2015
  • Accelerated spinal fusion in nude rats with human adult adipose-derived multipotent stromal cells (ASCs) and syngeneic deminieralized bone matrix (DBM), Lopez, Mandi; Fargason, Carmel; Kelly, Laura; Del Piero, Fabio; Dasa, Vinod; King, Andrew, 2014
  • Congestive heart failure in a harris hawk (Parabuteo unicinctus), Nevarez, Javier; Brandao, Joao; Beaufrere, Hugues ; Reynolds, Caryn; Johnson, Jimmy; Gaschen, Lorrie; Del Piero, Fabio; Tully, Thomas, 2013
  • Congestive heart failure in a harris hawk (Parabuteo unicinctus), Nevarez, Javier; Brandao, Joao; Beaufrere, Hugues ; Reynolds, Caryn; Johnson, Jimmy; Gaschen, Lorrie; Del Piero, Fabio; Tully, Thomas, 2013
Journal Article, Professional Journal:
  • Effects of plant-derived protein diets on the health of farmed American alligators (Alligator mississipiensis), DiGeronimo, Peter; Girolamo, Nicolas; Crossland, Nicolas; Del Piero, Fabio; Reigh, Robert; Nevarez, Javier, 2017, Journal of Zoo and Wildlife Medicine , Volume: 48, Number: 1, Pages: 131-135
  • Characterization of IgE-mediated cutaneous immediate and late-phase reactions in non-allergic horses, Woodward, Michelle; Pucheu-Haston, Cherie; Andrews, Frank; Kearney, Michael; Del Piero, Fabio, 2014, American Journal of Veterinary Research , Volume: 75, Number: 7, Pages: 633-641
  • A study for characterization of IgE-mediated cutaneous immediate and late-phase reactions in non-allergic domestic cats, Pucheu-Haston, Cherie; Seals, Shanna; Kearney, Michael; Del Piero, Fabio, 2014, Veterinary Immunology and Immunopathology , Volume: 159, Number: 1-2, Pages: 41-49
Other:
  • IHC-SOP-101.0 Microtomy of Embedded Tissue and Slide Preparation, Del Piero, Fabio; Bauer, Rudy, 2016
Editorial:
  • Equine multi-systemic eosinophilic epitheliotrophic disease (MEED), Pucheu-Haston, Cherie; Del Piero, Fabio, 2013