Dr. Antonieta Guerrero-Plata
Associate Professor
Pathobiological Sciences (PBS)

Research Interests:
Dr. Guerrero-Plata’s research interests are in the field of viral immunology focused on innate immunity, dendritic cells and respiratory viruses. Her work includes the study of the immune response to respiratory syncytial virus and human metapneumovirus, the most important cause of lower respiratory tract infections in children, elderly and immunocompromised patients. The long-term goal of her research is to develop new strategies to boost antiviral immunity and long-lasting protection against respiratory viral pathogens that cause significant airway morbidity. Additional studies in her laboratory are directed to determine the mechanisms by which environmental factors alter the frequency and severity of respiratory viral infections.

 Awards & Honors:
  • 2019 AAI Laboratory Travel Grant
  • 2019 Louisiana State University-Distinguished Dissertation Honorable Mention (Student: NR Cheemarla)
  • 2019 LSU School of Veterinary Medicine- Best Dissertation Award (Student: NR Cheemarla)
  • 2018 AAI Laboratory Travel Grant
  • 2016 AAI Laboratory Travel Grant
  • 2015 AAI Laboratory Travel Grant
  • 2013 AAI-Young Investigator Travel Grant- International Congress of Immunology
  • 2012 Carl Storm Fellowship-Gordon Research Conferences
  • 2012 Keystone Symposia Early Career Investigator Travel Award
  • 2008 AAI-Junior Faculty Travel Grant
  • 2008 ASV-International Congress of Virology Travel Grant
  • 2007 AAI-Junior Faculty Travel Award
  • 2007 ASV-Medical Virology Travel Grant
  • 2006 AAI-Huang Foundation Trainee Achievement Award
  • 2005 ATS-Minority Trainee Travel Award
  • 2004 Poster Award Winner-UTMB
  • 2002 James W. McLaughlin Fellowship-UTMB
  • 1998 Medal Alfonso Caso-UNAM
  • 1998 Scholarship to Distinguished Students to Study Abroad-Fundacion UNAM
  • 1997 Scholarship for PhD students-CONACyT
  • 1997 Scholarship for PhD Students-UNAM
  • 1996 Scholarship for MSc students-UNAM
  • 1995 Scholarship "Early Starting in Teaching and Research"-UNAM
  • 1994 Scholarship for MSc students-CONACyT
  • Other Harvard University
  • Postdoc The University of Texas Medical Branch
  • PhD Universidad Nacional Autonoma de Mexico
  • Visiting student- Imperial College London
  • MSc Universidad Nacional Autonoma de Mexico (UNAM)
  • Licensed Clinical Chemistry- Universidad Autonoma de Tamaulipas-Mexico
  • BS Universidad Autonoma de Tamaulipas
  • Center for Pre-Clinical Disease Research , National Institutes of Health - NIH, $11,192,691.00
  • Ex Vivo determination of platelet activation via flow cytometry and growth factor production in synovial fluid from osteoarthritic and non-osteoarthritic joints of horses, ACVS Foundation Diplomate Clinical Research Grant, $9,937.00
  • Characterization of Lung Dendritic Cell Phenotype in Response to Human Metapneumovirus Infection, Louisiana State University, $10,000.00
  • Regulatory role of ncRNA in human metapneumovirus infection, National Institutes of Health, $30,000.00
  • Molecular mechanisms of Viral Disease Enhancement by Tobacco Smoke Exposure, The Flight Attendant Medical Research Institute, $325,000.00
  • Mucosal Response in Human Metapneumovirus Infection, NIH/COBRE, $50,000.00
  • Role of Mucin 19 Response in Respiratory Viral Infections, The American Association of Immunologists, $50,112.00
  • Molecular Analysis of Respiratory Syncytial Virus Infection in Immune Cells, LSU Board of Regents, $10,000.00
  • Regulatory Mechanisms of The Immune Response by Respiratory Paramyxovirus Infection, Louisiana State University, $10,000.00
Journal Article, Academic Journal:
  • The Importance of miRNA Identification During Respiratory Viral Infections, Martinez-Espinoza, Ivan; Banos-Lara, MDR; Guerrero-Plata, M, 2021, Journal of Cellular Immunology , Volume: 3, Number: 4, Pages: 207-2014
  • Human Metapneumovirus Induces Mucin 19 Which Contributes to Viral Pathogenesis, McBride, Kaitlin; Banos-Lara, MDR; Cheemarla, Nagarjuna; Guerrero-Plata, M, 2020, Pathogens , Volume: 9, Number: 9, Pages: 1-12
  • In utero tobacco exposure alters lung inflammation, viral clearance and CD8 T cell responses in neonatal mice infected with respiratory syncytial virus, Cheemarla, Nagarjuna; Uche, Ifeanyi; McBride, Kaitlin; Naidu, Shan; Guerrero-Plata, M, 2019, Am J Physiol Lung Cell Mol Physiol , Volume: 317, Number: 2, Pages: L212-L221
  • Interferon-Mediated Response to Human Metapneumovirus Infection, Uche, Ifeanyi; Guerrero-Plata, M, 2018, Viruses , Volume: 10, Number: 9, Pages: 1-15
  • Comparative Analysis of miRNA profile in human dendritic cells infected with respiratory syncytial virus and human metapneumovirus , Banos-Lara, Ma.; Zabaleta, Jovanny; Garai, Jone; Badoo, Melody; Guerrero-Plata, M, 2018, BMC Research Notes , Volume: 11, Pages: 1-7
  • How does the Human Metapneumovirus Regulate Infiltration into the Airways?, Cheemarla, Nagarjuna; Guerrero-Plata, M, 2018, Future Virology , Volume: 13, Number: 4, Pages: 233-235
  • Human Metapneumovirus Attachment Protein Contributes to Neutrophil Recruitment into the Airways of Infected Mice, Cheemarla, Nagarjuna; Guerrero-Plata, M, 2017, Viruses , Volume: 9, Number: 10, Pages: 9
  • Respiratory syncytial virus vaccine approaches: current overview, Clark, Carolyn; Guerrero-Plata, M, 2017, Current Clinical Microbiology Reports , Volume: 4, Number: 4, Pages: 202-207
  • Neutrophils Regulate the Lung Inflammatory Response via gd T Cell Infiltration in an Experimental Mouse Model of Human Metapneumovirus Infection, Cheemarla, Nagarjuna; Banos-Lara, Rocio; Naidu, Shan; Guerrero-Plata, M, 2017, Journal of Leukocyte Biology , Volume: 101, Number: 16, Pages: 1383-1392
  • Immune Response to Human Metapneumovirus: What we have learned from the Mouse Model, Cheemarla, Nagarjuna; Guerrero-Plata, M, 2015, Pathogens , Volume: 4, Number: 3, Pages: 682-696
  • Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells, Banos-Lara, Ma; Piao, Boyang; Guerrero-Plata, M, 2015, Mediators of Inflammation , Volume: 2015, Number: 2015, Pages: 1-7
  • Impact and Regulation of Lambda Interferon Responses in Human Metapneumovirus Infection, Banos-Lara, Rocio; Harvey, Lindsey ; Mendoza, Alex; Simms, Dawn; Chouljenko, Vladimir; Wakamatsu, Nobuko; Kousoulas, Konstantin; Guerrero-Plata, M, 2015, Journal of Virology , Volume: 89, Number: 1, Pages: 730-742
  • Dendritic Cells in Human Pneumovirus and Metapneumovirus Infections, Guerrero-Plata, M, 2013, Viruses , Volume: 5, Number: 6, Pages: 1553-1570
  • Critical Role of MDA5 in the Interferon Response Induced by Human Metapneumovirus Infection in Dendritic Cells and in Vivo, Banos-Lara, Rocio; Ghosh, Arpita; Guerrero-Plata, M, 2013, Journal of Virology , Volume: 87, Number: 2, Pages: 1242-51
  • Interleukin-12p40 Modulates Human Metapneumovirus-induced Pulmonary Disease in an Acute Mouse Model of Infection, Chakraborty, K; Zhou, Z; Wakamatsu, Nobuko; Guerrero-Plata, M, 2012, PLoS One , Volume: 7, Number: 5, Pages: e37173
  • The Monomer-dimer Equilibrium and Glycosaminoglycan Interactions of Chemokine CXCL8 Regulate Tissue-specific Neutrophil Recruitment, Gangavarapu, P; Rajagopalan, L; Kolli, D; Guerrero-Plata, M; Garofalo, R; Rajarathnam, K, 2012, Journal of Leukocyte Biology , Volume: 91, Pages: 259-265
  • Isolation of mouse lung dendritic cells, Lancelin, W; Guerrero-Plata, M, 2011, Journal of Visualized Experiments , Volume: 57, Number: pii:3563, Pages: 1-4
  • Cigarette smoke suppresses TLR-7 stimulation in response to virus infection in plasmacytoid dendritic cells, Castro, S; Chakraborty, K; Guerrero-Plata, M, 2011, Toxicology in Vitro , Volume: 25, Number: 5, Pages: 1106-13
  • Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment, Das, S; Rajagopalan, L; Guerrero-Plata, M; Sai, J; Richmond, A; Garofalo, R; Rajarathnam, K, 2010, PLoS One , Volume: 5, Number: 7, Pages: e11754