Dr. Antonieta Guerrero-Plata
Associate Professor
Pathobiological Sciences (PBS)

Research Interests:
Dr. Guerrero-Plata’s research interests are in the field of viral immunology focused on innate immunity, dendritic cells and respiratory viruses. Her work includes the study of the immune response to respiratory syncytial virus and human metapneumovirus, the most important cause of lower respiratory tract infections in children, elderly and immunocompromised patients. The long-term goal of her research is to develop new strategies to boost antiviral immunity and long-lasting protection against respiratory viral pathogens that cause significant airway morbidity. Additional studies in her laboratory are directed to determine the mechanisms by which environmental factors alter the frequency and severity of respiratory viral infections.

 Awards & Honors:
  • 2016 AAI Laboratory Travel Grant 2016
  • 2015 AAI Laboraory Travel Grant
  • 2013 AAI-Young Investigator Travel Grant- International Congress of Immunology
  • 2012 Carl Storm Fellowship
  • 2012 Keystone Symposia Early Career Investigator Travel Award
  • 2008 Junior Faculty Travel Grant
  • 2008 International Congress of Virology Travel Grant
  • 2007 Junior Faculty Travel Award
  • 2007 Medical Virology Travel Grant
  • 2006 AAI-Huang Foundation Trainee Achievement Award
  • 2005 Minority Trainee Travel Award
  • 2004 Poster Award Winner
  • 2002 James W. McLaughlin Fellowship
  • 1998 Medal Alfonso Caso
  • 1998 Scholarship to Distinguished Students to Study Abroad
  • 1997 Scholarship for PhD students
  • 1997 Scholarship for PhD Students
  • 1996 Scholarship for Master in Science students
  • 1995 Scholarship "Early Starting in Teaching and Research"
  • 1994 Scholarship for Master in Science student
 Education:
  • PhD Universidad Nacional Autonoma de Mexico
  • Visiting student Imperial College London
  • MSc Universidad Nacional Autonoma de Mexico
  • BS Universidad Autonoma de Tamaulipas
 Grants:
  • Molecular mechanisms of Viral Disease Enhancement by Tobacco Smoke Exposure, The Flight Attendant Medical Research Institute, $325,000.00
  • Mucosal Response in Human Metapneumovirus Infection, NIH/COBRE, $50,000.00
  • Role of Mucin 19 Response in Respiratory Viral Infections, The American Association of Immunologists, $50,112.00
  • Molecular Analysis of Respiratory Syncytial Virus Infection in Immune Cells, LSU Board of Regents, $10,000.00
  • Regulatory Mechanisms of The Immune Response by Respiratory Paramyxovirus Infection, Louisiana State University, $10,000.00
 Publications:
Journal Article, Academic Journal:
  • How does the Human Metapneumovirus Regulate Infiltration into the Airways?, Guerrero-Plata, M; Cheemarla, Nagarjuna, 2018, Future Virology
  • Human Metapneumovirus Attachment Protein Contributes to Neutrophil Recruitment into the Airways of Infected Mice, Guerrero-Plata, M; Cheemarla, Nagarjuna, 2017, Viruses , Volume: 9, Number: 10, Pages: 9
  • Respiratory syncytial virus vaccine approaches: current overview, Clark, Carolyn; Guerrero-Plata, M, 2017, Current Clinical Microbiology Reports , Volume: 4, Number: 4, Pages: 202-207
  • Neutrophils Regulate the Lung Inflammatory Response via gd T Cell Infiltration in an Experimental Mouse Model of Human Metapneumovirus Infection, Guerrero-Plata, M; Naidu, Shan; Banos-Lara, Rocio; Cheemarla, Nagarjuna, 2017, Journal of Leukocyte Biology , Volume: 101, Number: 16, Pages: 1383-1392
  • Immune Response to Human Metapneumovirus: What we have learned from the Mouse Model, Guerrero-Plata, M; Cheemarla, Nagarjuna, 2015, Pathogens , Volume: 4, Number: 3, Pages: 682-696
  • Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells, Guerrero-Plata, M; Banos-Lara, Ma; Piao, Boyang, 2015, Mediators of Inflammation , Volume: 2015, Number: 2015, Pages: 1-7
  • Impact and Regulation of Lambda Interferon Responses in Human Metapneumovirus Infection, Guerrero-Plata, M; Mendoza, Alex; Banos-Lara, Rocio; Harvey, Lindsey ; Simms, Dawn; Chouljenko, Vladimir; Kousoulas, Konstantin; Wakamatsu, Nobuko, 2015, Journal of Virology , Volume: 89, Number: 1, Pages: 730-742
  • Dendritic Cells in Human Pneumovirus and Metapneumovirus Infections, Guerrero-Plata, M, 2013, Viruses , Volume: 5, Number: 6, Pages: 1553-1570
  • Critical Role of MDA5 in the Interferon Response Induced by Human Metapneumovirus Infection in Dendritic Cells and in Vivo, Guerrero-Plata, M; Banos-Lara, Rocio; Ghosh, Arpita, 2013, Journal of Virology , Volume: 87, Number: 2, Pages: 1242-51
  • Interleukin-12p40 Modulates Human Metapneumovirus-induced Pulmonary Disease in an Acute Mouse Model of Infection, Zhou, Z; Guerrero-Plata, M; Wakamatsu, Nobuko; Chakraborty, K, 2012, PLoS One , Volume: 7, Number: 5, Pages: e37173
  • The Monomer-dimer Equilibrium and Glycosaminoglycan Interactions of Chemokine CXCL8 Regulate Tissue-specific Neutrophil Recruitment, Guerrero-Plata, M; Gangavarapu, P; Rajagopalan, L; Garofalo, R; Rajarathnam, K; Kolli, D, 2012, Journal of Leukocyte Biology , Volume: 91, Pages: 259-265
  • Isolation of mouse lung dendritic cells, Guerrero-Plata, M; Lancelin, W, 2011, Journal of Visualized Experiments , Volume: 57, Number: pii:3563, Pages: 1-4
  • Cigarette smoke suppresses TLR-7 stimulation in response to virus infection in plasmacytoid dendritic cells, Guerrero-Plata, M; Castro, S; Chakraborty, K, 2011, Toxicology in Vitro , Volume: 25, Number: 5, Pages: 1106-13
  • Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment, Guerrero-Plata, M; Das, S; Rajagopalan, L; Sai, J; Richmond, A; Garofalo, R; Rajarathnam, K, 2010, PLoS One , Volume: 5, Number: 7, Pages: e11754